Seasoned wicketkeeper-batsman Dinesh Karthik was called as a replacement for the injured Pandey.
He last played for India in the second T20I against England in January earlier this year.
Indian middle-order batsman Manish Pandey has been ruled out of next month's ICC Champions Trophy due to a side strain and will be replaced in the squad by wicketkeeper-batsman Dinesh Karthik, the BCCI announced on Thursday.
India play arch-rivals Pakistan on June 4 to begin their defense of the Champions Trophy.
Karthik was out for a duck in Gujarat Lions' loss to Sunrisers Hyderabad to sign off on their IPL existence, but he made 40, 35 not out and 65 in his three previous innings at the Twenty20 tournament. He scored 704 runs in the 2016-17 Ranji Trophy at 54.15, with one hundred and five fifties, and was a vital cog in Tamil Nadu's run to a 50-overs title double, scoring a combined 854 runs at 85.40 in the Vijay Hazare Trophy and Deodhar Trophy.
Incidentally, Karthik was a part of the Indian team which won the Champions Trophy, back in 2013. He has amassed 1,000 runs in Tests, 1,313 in ODIs and 100 in T20Is.
Virat Kohli (C), Shikhar Dhawan, Rohit Sharma, Ajinkya Rahane, Mahendra Singh Dhoni (wk), Yuvraj Singh, Kedar Jadhav, Hardik Pandya, R Ashwin, R Jadeja, Mohd. He scored two centuries in two matches against Sri Lanka and Australia to help India achieve victories against both teams.